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So when I had my recent check up I was expecting to change, and hoping that a new set of side effects would at least be something different to deal with, if not better. You've heard so many women talk about how they put on weight while . I am Stage 2a Grade 2, Oncotype 17, post menopausal and did a lumpectomy and radiation, with no chemo. (Obviously this third scenario is the one I cross my fingers for.) It started 12 days ago, about 48 hours after my oncologist asked me to stop taking Tamoxifen for six weeks. The survey involved 400 healthy women at a higher risk of breast cancer from 20 centers across England. At that time they plan to take a 2-3 month break from Tamoxifen, then try to conceive (TTC) using in vitro fertilization (IVF) with the eggs they froze at the fertility clinic before she began . Patients with low-risk disease are often prescribed tamoxifen, and at year five, they can continue on tamoxifen for another five years if they are still premenopausal. For the past two months my hot flashes had become an hourly occurrence, making my entire body feel like it was . Tamoxifen and blood clots. Pregnancy After Breast Cancer: Steph's Story - Rethink ... Same body aches I've tolerated since taking Tamoxifen. Hormonal Therapy: Managing Side Effects in Women - Health ... Nolvadex (Tamoxifen Citrate) - How to use it for your PCT 2020 I am on day 2 and I am a different person. By Jigna Shah Jimenez March 31, 2017. In my case, these are the cards I've been dealt, and I won't be able to get the answers I need by the time I need them. I'm at the end of my patience. Tamoxifen conundrum - Cancer Chat Osteoporosis is a disorder in which bones become porous and break more easily. The message for women from this long-term follow-up study is "To take your pills for as long as they're prescribed," concluded Dr. Ford. Setting 2 hospitals from a single health board in Scotland. TTC on a tamoxifen break following breast cancer diagnosis ... Next switched to Tamoxifen (6 months) - took a self-imposed break for a month when my son got married (felt so much better). Some people take tamoxifen to lower the risk of developing breast cancer. and finally #4 Tamoxifen. It works by binding itself to estrogen receptors in the mammary tissue, which prevents the cancer cells from feeding off the hormone in these areas. While long-term tamoxifen use among breast cancer survivors decreases their risk of developing the most common, less aggressive type of second breast cancer, such use is associated with a more . Taking a Break From Letrozole Therapy After Breast Cancer. "Five years of therapy confers benefits for up to 15 years—the benefits last far . It can greatly reduce the risk of cancer recurrence and invasive cancer. Hormone Therapy Q&A with Dr. Rachel Jankowitz - The ... Green Tea and Tamoxifen - Advanced breast cancer But better adherence should be executed. I have recently stopped taking my tamoxifen to try for my first baby. Ask an Expert: Tamoxifen vs. Arimidex? | Providence Oregon SE not quite as bad but still intolerable. Potential side effects and risks If you experience side effects and decide to take a break from taking tamoxifen, it is likely that the side . Six years later I had a recurrence show up. The Choice to Walk Away From Aromatase Inhibitors The daily oral medication stops cancer cells from using estrogen and progesterone to grow and spread. Q: I recently finished treatment for breast cancer. Then there's chemo-resistance, when cancer cells grow accustomed to a treatment and become resistant — eventually making the drug less effective. After 3 months Of feeling great, going none stop. It is amazing. Not only did my use effects come back, but I had a whole new set of them on top of it. Going to have cholesterol rechecked in Oct. Results indicate that almost a third (29%) of the women believe physicians prescribe too many medicines, and more than a third (35% . I haven't been lucky enough to conceive as yet and hoping against hope that it will happen soon. It had been somewhat manageable until about a couple month ago . Women are choosing to make informed decisions. If I take 5 years of Tamoxifen it should go down to 5%. I was not tested for CYP2D6 to see if I metabolize tamoxifen. lower back or side pain. One way to do this is to make it a habit to take your medicine same time everyday: it could be timed as the first thing or the last thing you do daily. It can greatly reduce the risk of cancer recurrence and invasive cancer. Reluctantly, you began the unknown path. So, on to the Femara. Nolvadex is the trade name for 'Tamoxifen Citrate', a Selective Estrogen Receptor Modulator (SERM) that has for long been used for the treatment of hormone-receptor positive breast cancer. Participants were asked about their views of taking tamoxifen, as well as other concerns about medication. I'm supposed to take tamoxifen daily for 5 years. The side effects are now too much. For most side effects, taking tamoxifen made no difference, but tamoxifen did increase the chance of experiencing some side effects, which are described on the following pages. It doesn't have any estrogen-like effects, so women taking this drug have more bone thinning and fractures. I do not want to have to take anti-depressants too! She then began taking tamoxifen before switching to an aromatase inhibitor (AI). TTC on a tamoxifen break following breast cancer diagnosis. what happen if i missed a day, a week or more? Women who have gone through menopause have a higher risk for bone loss. I refused the AI as I heard the side effects of joint pain were bad. My questions: 1. Taking low-dose tamoxifen lowered the risk of recurrent or new breast cancer by 52 percent, the researchers reported. If you're sexually active with a chance of becoming pregnant, your specialist is likely to advise you use a non-hormonal method of contraception while taking . I have been taking it for almost a year and recently my hair has - Answered by a verified Doctor. And the rates of side effects were similar between the two groups. One of the options is to take a break for 6 weeks, get clean blood tests to confirm I am def in menopause & then start on Letrozole for 6 years. Tamoxifen is an effective hormone therapy used to treat hormone receptor-positive breast cancer. After a stage IIb breast cancer diagnosis in 1999, Margaret had surgery, chemotherapy and radiation therapy. Dr. Sewa Legha answered. So recently I took a break from tamoxifen against my new onc wishes, (he is a drug pusher) doesn't listen to a word I'm saying. You can use the study as a second opinion to make health care decisions. Both of these are valid questions. I went back on Tamoxifen for a couple of months and then started having depression along with the aches, hot flashes, etc. When does this end. When I first started on tamoxifen a little over 2 1/2 years ago, I was told that I would have 2 -3 years on it, and then switch to arimidex. Design Qualitative study using semistructured, one-to-one interviews. painful or difficult urination. Tamoxifen helps to stop cancer from returning if it's taken over a long period But it is known to cause side effects including hot flushes, sweats and nausea And a third of women do not take the . You not only survive but thrive through surgery after surgery. No longer do they blindly follow the advice of doctors to take medication for the next five to 10 years that may or may not prevent the recurrence of breast cancer. Evening everyone, I have been on Tamoxifen for four years and I have just had a six week break from it, so blood tests could be done to check hormone levels plus other tests. Hi there. Kids back to school and I started back into my old routines as much as possible. ©2008 The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Blvd, Houston, TX 77030 1-800-392-1611 (USA) / 1-713-792-6161 I'm feeling pretty terrified but just so weak that I really want to boost myself before going on again and more importantly get some QOL. Taking tamoxifen while pregnant may be harmful to a developing baby. Take care and best wishes There's no right or wrong answer it is what is best for you BTW The BCNA website is a great resource for understanding and formulating questions. About a month ago I started taking Tamoxifen. Or not. Hi, Sorry I have been away a bunch. Tamoxifen helps to stop cancer from returning if it's taken over a long period But it is known to cause side effects including hot flushes, sweats and nausea And a third of women do not take the . This is the enzyme, found in the liver, that breaks down tamoxifen into its active compounds. pale skin. Objective To explore women's experiences of taking adjuvant endocrine therapy as a treatment for breast cancer and how their beliefs about the purpose of the medication, side effects experienced and interactions with health professionals might influence adherence. Most people who take letrozole will have had surgery, radiotherapy or sometimes chemotherapy to treat their breast cancer first. 41 possible side effects. You feel confident you have beaten the Cancer and while that may be true, you have a five-year journey ahead called tamoxifen. Medical Oncology 50 years experience. For now, if i can offer any advice its take a break from the dutasteride, i know for a fact that dutasteride half life is ALOT longer than finasteride so you may need an extended break. It is mainly prescribed for women who have been through the menopause and have a type of cancer called "hormone-dependent" breast cancer.. And, If I do, is there anything I can do to stop it—and actually lose weight? While most women take tamoxifen for 5 or 10 years, it hasn't been clear if taking tamoxifen for fewer than 5 years offered benefits. The phase IV clinical study analyzes what interactions people who take Mucinex and Tamoxifen citrate have. A Swedish study suggests that taking tamoxifen for 2 years offers long-term survival benefits for premenopausal women diagnosed with early-stage, estrogen-receptor-positive disease compared to no treatment after . Or, if they become clearly postmenopausal while on tamoxifen and/or are postmenopausal at year five, they have the option to switch to an aromatase inhibitor. yes, taking a break from tamoxifen for 2-3 weeks and see if your symptoms get better. This started about 4 months ago and well into tamoxifen again. If you are not sure when to start taking this drug, talk with your doctor. All typical side effects of body aches were the same as being on Tamoxifen. rapid, shallow breathing. I'm really seriously questioning whether it's worth it. I'd just finished telling him how the drug's symptoms had escalated again and I was at my wit's end. But, I've already discussed a one month off, two months on regime with my oncologist if I can't tolerate the Femara on a daily basis. Others may worry about tamoxifen's rare side effects, including blood clots and increased risk of uterine cancer. #3 Radiation. that is one way to test if the tamoxifen is causing it. And the rates of side effects were similar between the two groups. Barks34 Member Posts: 39 . There seems to be an increased risk of fetal abnormalities when taking tamoxifen during pregnancy (12.6% in contrast to 3.9% in the general population), but the evidence is limited and no causal relationship could be established. I (37F) finished my active treatment for Stage 1 hormone + BC last year and was prescribed Lupron monthly and Exemestane. Margaret Andrews couldn't wait to be done with hormonal therapy: treatment for hormone receptor-positive breast cancer, which grows because of the hormones estrogen or progesterone. Life After Tamoxifen. Women with hormone-sensitive breast cancer face years of adjuvant therapy with antiestrogen drugs, with the latest data suggesting that . "Breast cancer" - you accept the diagnosis! I have had a mastectomy, chemo and another mastectomy is planned this year, was on Tamoxifen but suffered enormously from its side effects so currently taking a break and seriously considering staying off it altogether. So if you take 10,000 women who take tamoxifen for breast cancer, alright, then you will increase the risk of getting endometrial cancer from three in 10,000 for women who don't take tamoxifen to . I can't take Tamoxifen because I've already had surgery for a blocked carotid artery and the chance of stroke and/or blood clots would be extremely high in my case. 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